Abstract: One of the important contents of the interpretation of the eco-geological interaction model is to visua-lize the weathering and soil-forming process of bedrock and its impact on ecology, including bedrock type, characteristics and migration rules of soil-forming elements in the weathering process, soil structure, and corresponding ecological characteristics. The impact of epigenetic geological processes such as bedrock weathering and soil formation on ecological characteristics is highlighted. In this paper, taking the northern Yinshan of Inner Mongolia, Zhangbei Dam and typical karst area in Southwest China, the authors analyzed the processes and characteristics of bedrock weathering and soil formation under the different supergene geological condition, such as the vertical structure characteristics and material composition of soil, migration characteristics of element, and element enrichment and loss of ecological support layer, and their influence on ecological distribution characteristics. Three eco-geological interaction models are established, including the vegetation distribution and wind erosion bedrock weathering and soil-forming model, artificial forest degradation and weathering alluvial proluvial soil chestnut calcification model in depression basin, and the influence model of soil-forming parent rock on the development degree of rocky desertification. This research helps to reveal the influence of soil-forming process on vegetation distribution and ecological problems, and provides scientific basis for land and space ecological protection and restoration.