Abstract: The study of the spatial distribution characteristics and law of Quaternary sedimentary strata in Zhengzhou is closely related to the birth and development of early human civilization along Yellow River, especially in the surrounding areas of Zhengzhou. And, it also plays an important supporting role in modern urban planning and layout, underground space development and utilization, as well as the ecological protection and high-quality development of Yellow River. Thus, the geological tourism and geological cultural resources survey was carried out in Zhengzhou, and 38 sedimentary boreholes were drilled in the main urban area of Zhengzhou and different geomorphic units around it, including 9 deep boreholes exposing Quaternary period. Based on the results of deep drilling and existing HKGA borehole exploration results, the authors established the standard stratigraphic columns of various geomorphic units, through accurately dividing the Quaternary sedimentary stratigraphic structure of each borehole. By analyzing and comparing the changing characteristics of sedimentary strata in these different geomorphic units, the authors obtained the understanding and empirical evidence, that is aeolian sedimentation was commonly present in Early and Middle Pleistocene in the eastern plain area, and it transformed into river and lacustrine facies sedimentation in Late Pleistocene. Based on the analysis of sediment source characteristics, it has indirectly confirmed that the sedimentation time of Yellow River sediment in this area may have started from the Late Pleistocene period.