Abstract: After summarizing the main progress and achievements of uranium resource investigation and evaluation, and after analyzing the regional metallogenic condition, we proposed that the Xuemisitan volcanic belt of Xinjiang province had favorable uranium metallogenic geological background. We summarized the characteristics of uranium mineralization in different regions according to the ore-controlling factors, such as the Baiyanghe uranium polymetallic deposit was controlled by the sub-volcanic contact zone, the Yinisala-Shiyuegongqu uranium ore concentration area was controlled by the secondary fissure zone, and the Mamente uranium ore occurrence was controlled by the collapsed volcanic apparatus. Combining with the geological conditions and the existing geological work, we forecasted the uranium prospecting areas, pointed out the future prospecting direction and proposed the following work suggestions