Abstract: Zaozigou gold deposit is located in the northwest of West Qinling orogenic belt, with well-developed vegetation and poor bedrock outcropping. The geochemical exploration is one of the most effective exploration methods in the region. On the basis of systematically combing the geochemical characteristics of 1:200,000 and 1:50,000 water sediment measurements and 1:10,000 soil measurements of Zaozigou gold deposit, the authors found that Au has a positive correlation with Sb, As, Hg, Ag and Cu, combined with the characteristics of the primary halo of the deep borehole SK8314. Especially, the combination of Au and Sb is a direct geochemical marker for gold prospecting. The deep primary halo zoning sequence is Bi-Cu-Mo-Sb-Ag-Au-W-As-Sn-Zn-Cd-Pb-Cr-Ni-Co-Hg, and Bi is located in the leading halo of the zoning sequence. Cu is located in the leading halo of the zoning sequence, and Pb and Zn are located in the tail halo of the zoning sequence, indicating that the ore body has the characteristics of multi-stage metallogenic superposition, probably with blind ore body in the depth. At the same time, the ratios of geochemical parameters (As+Sb)/(Bi+Mo) and 100·Sb/(Bi·Mo) gradually increased with the increasing depth at hole SK8314 below 1 850 m, indicating blind ore bodies in the deeper part and a large prospecting space. The research results could provide some references for deep and peripheral prospecting in Zaozigou.