Abstract: The hydrogen surface anomalies were widespreadly discovered and the genesis mechanism and accumulation mechanism of underground hydrogen were deeply understood. As a clean energy, the natural hydrogen is expected to become a key energy source for global energy transition and carbon neutrality due to its huge resource potential and renewable nature. Through the tracking of the latest progress in global natural hydrogen exploration and development, it is concluded that natural hydrogen has become a hot topic in the global geology and energy fields, and the resource surveys and discoveries of natural hydrogen driven by multiple genesis mechanism have extensive and multi-point characteristics. The global development of natural hydrogen was driven by continuous investment of major countries as Europe and the United States. Besides, the hydrogen and helium have the potential of “co-exploration and co-exploitation”. In view of the preliminary progress in natural hydrogen resources discovery in China and the preliminary assessment of accumulation conditions and favorable zones, it is suggested that China should carry out the nationwide natural hydrogen resource survey and evaluation as soon as possible.