Abstract: Under the general requirement of highlighting the concept of ecological civilization during international cooperation in construction, China and Myanmar are facing challenges in jointly promoting infrastructure development, such as low water resources carrying capacity, weak foundation of groundwater development and environmental protection. The authors in this paper systematically analyzed the groundwater occurrence conditions and groundwater environmental issues in different hydrogeological units in Myanmar, and revealed uneven potential for groundwater resources development and utilization in different regions of Myanmar. In the central plateau, alluvial and Ayeyarwady Group aquifers have high groundwater potentiality, while Pegu Group and Eocene aquifers have certain potentiality in groundwater utilization. In the eastern highland region, the hydrogeological conditions of karst groundwater are complex and difficult to develop and utilize. In the western, southeastern coastal and delta regions, the groundwater exploitation is severely limited by environmental groundwater problems such as high salinity and arsenic content. This research contributes to a systematic understanding of the hydrogeological conditions across Myanmar and provides scientific basis for promoting rational planning and exploitation of groundwater resources in Myanmar.