Abstract: Exploration work has newly discovered zinc polymetallic deposit in Tangcunxu,Nanling County, An hui Province. Three zinc lead ore (mineralized) bodies and one molybdenum ore body have been delineated after drilling verification and analysis testing. The geological characteristics and deposit characteristics of the mining area were summarized, and it is found that the Zn ore is controlled by Wutong Formation in Devonian and Huang-longchuanshan Formation in Carboniferous. Besides, the Zn ore is closely related to the intrusion of brecciform granodiorite porphyry and damaged by fault F₂, while the Mo ore body is formed inside the granodiorite. It is considered that the east area of fault F₂ is the favorable position for the extension of the Zn ore body in NW direction, and the deep area around ZK104 borehole is the important position for Cu and Mo ore. The west area of fault F₂ is the favorable position to search for contact metasomatic ore body, which provides a new idea for the prospecting work in this area.