Abstract: The Early Devonian monzogranite was reported for the first time in Xiarihamu area of East Kunlun, so the authors investigated its geochronological and geochemical characteristics to further explore the petrogensis and tectonic setting. The U-Pb of zircon age of the monzogranite is (412.1 ± 5.7) Ma (MSWD = 0.95), which formed in early Early Devonian, and the monzogranite belongs to slightly peraluminous subalkaline series. The monzogranite is characterized by high SiO₂ (71.41% ~ 72.46%) and K₂O (5.27% ~ 6.16%), low Fe₂O₃(1.86% ~ 2.05%) and P₂O₅(0.08% ~ 0.12%), and high LREE with obvious negative Eu anomalies. Rb, Th, Zr and Hf are obviously enriched, while Nb, Sr, P, Ti and Ba are strongly depleted on the primitive mantle-normalized trace element spider diagram. The monzogranite in Xiarihamu area belongs to I-type granite, and the magma of the source rock may come from the partial melting of the lower crust materials caused by the underplating heating of mantle-derived magma. The monzogranite was formed in the tectonic environment of syn-collision converting to post-collision, suggesting that Xiarihamu area of East Kunlun had been in the post-orogenic extension stage since early Early Devonian.