Abstract: Through the 1∶50 000 helicopter aeromagnetic survey, the authors investigated the saving status and distribution characteristics of intrusive rock and skarn iron ore in deep coverage area of Qihe in Shandong Province. Based on the high precision aeromagnetic data and the geology and drill hole data, the authors studied the aeromagnetic anomaly and the fracture distribution character of magmatic rock in this area, and compiled the stratigraphic structure deduced from aeromagnetic data in Qihe of Shandong Province. According to the study of magnetic iron ore ΔT abnormal curve characteristics for different scale and burial depth in deep coverage area, aeromagnetic ΔT abnormality comparison result and the human-computer interactive inversion of aeromagnetic ΔT in important section L8040, the aeromagnetic field characters in deep coverage area were acquired and the geological and geophysical ore prospecting marks were built. Besides, the ore-forming favorable areas were also predicted. Seven iron ore prospecting areas and eight iron ore prospecting targets were determined and the amount of iron ore resources was predicted to be 150 million tons. This research has reference significance for basic geological research and deep coverage iron ore prospecting in Qihe of Shandong Province.