Abstract: Geochemical survey results have been used widely and maturely in mineral exploration work. In order to ascertain the geochemical indication information of mineralization and prospecting in the north of Chongli, the authors made a comprehensive analysis of the stream sediment survey and the anomaly verification results in this area. Through calculating element enrichment coefficient and variation coefficient, analyzing R-type cluster, counting the rocks geological ages in the geochemical prospecting anomaly area, and comparing the mineralization factors of geochemical prospecting anomaly, the deposits known and the typical deposits, the authors deduced that the main prospecting elements in this area are Ag, Pb, Zn, Mo and Cd, and the two element groups (Ag, Pb, Zn and Mo, W) have co-associated relationship respectively. And they pointed out that the geochemical prospecting anomaly in the area is mainly controlled by magmatic hydrothermal fluid of Yanshanian. After comprehensive analysis, the authors considered that the prospecting model in this area is the sub-volcanic-hydrothermal polymetallic deposit as Caijiaying deposit, and there is potential to find sub-volcanic-hydrothermal Ag, Pb, Zn, Mo polymetallic deposits in this area.