Abstract: In recent years, the “Comprehensive Geological Environment Survey Project in Pan-Pearl River Delta region” organized and implemented by the China Geological Survey has achieved a number of important achievements and knowledge. The authors have combed the advantages of resources and environment conditions for green development in pan-Pearl River Delta region. The advantages include the following points: ①The advantages of selenium-rich arable land resources are obvious, which can effectively support the development of selenium-rich industry; ②The groundwater resources are abundant, the water quality is generally excellent, and the emergency/reserve water supply capability is strong; ③There are many types of typical and rare geological relics with high value, which can boost the development of tourism industry; ④There are a great number of geothermal resources, which are conducive to the layout and development of clean energy industry; ⑤The coastal zone has superior resources, but there are some geological environment problems such as coastal erosion and silting; ⑥The regional characteristics of mineral resources are distinct, and there is a great potential for the development of offshore energy resources; ⑦The overall engineering geological conditions are good. This paper points out some major geological environment problems that need to be paid attention to, such as local landslide geological disasters, karst collapse, water and soil pollution and ground subsidence. The authors found that the high background value of selenium in the soil of Pearl River estuary was the basis of the formation of selenium-rich rice, and probed the favorable areas for water exploration in the pressure tectonic zone of the red bed basin and the coordination degree between economic and social development and green and ecological environment in the process of urban agglomeration of Pan-Pearl River Delta. These progresses could provide support for regional territorial space planning, green industry development and ecological environment protection.