Abstract: Fluorite ore is a dominant mineral in Hunan Province, because of large resource, multifarious types, a long history of development and great prospecting potential. With the growing demand of fluorite ore at home and abroad, important practical significance has shown in further study of controlling factors and enrichment regularity of fluorite ore. This paper introduces metallogenic geological background, resource characteristics, ore-controlling factors and fluorite ore types in Hunan Province. On the basis of the actual geological data, this paper analyzes the mineralization distribution of fluorite ore, summarizes the metallogenic geological characteristics of fluorite ore, and divides the metallogenic series of fluorite deposits. The further prospecting work of fluorite deposit includes mineral resources potential evaluation, mineral survey and exploration in Hunan Province.